Center for Cardiovascular and Pulmonary Research
- Read about the center's mission, areas of focus, projects and more.
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Research Beat
- The Center for Cardiovascular and Pulmonary Research newsletter "Research Beat" includes a message from the Director and updates about the Center's newest research.
- Read the latest edition »
Research Study: Genetics of Left Ventricular Outflow Tract Malformations
- Do you have a family member who has been diagnosed with a heart defect? We invite them to participate in our research study.
- Learn how »
Research Advances
The Center for Cardiovascular and Pulmonary Research at The Research Institute at Nationwide Hospital provides laboratory-based research, pre-clinical studies and translational research in pediatric cardiology. Research is directed at:
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Improving therapies for pediatric cardiovascular diseases
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Enhancing outcomes for infants, children and adolescents with heart disease
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Fostering prevention of pediatric cardiovascular disease
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Promoting cardiovascular health among adults
Detailed and comprehensive study at the molecular, cellular and pathophysiological levels are crucial to improving diagnosis and treatment of cardiovascular disease in children, and quite possibly hold the key to prevention in adults. The Centr seeks to identify mechanisms and risk factors associated with initiation and/or progression of cardiovascular disease in children, define differences and similarities between pediatric and adult disease mechanisms, and ultimately optimize therapies and strategies for prevention of heart disease.
Active collaborative projects with The Ohio State University include examination of the role of oxidants and mitochondria in sepsis-related cardiac failure, vascular endothelial growth factors (VEGF) transcript variation and angiogenesis, mechanisms of HIV-related cardiomyopathy and molecular approaches for antioxidant protection.
